Which one is the best?Or it can provide what I am interested when using Twitter? I sorted a list of various applications created with Adobe AIR.You can find out which of them are cross-platform, only for Mac, iPhone or Linux. I tried to highlight the known ones but I might have missed a few.All in all I hope you like the list.

Cross-platform Apps

1. Ada
Ada is the perfect little Twitter app with a clean, compact design

2. AlertThingy
AlertThingy v3 brings the very latest updates from your favourite social networks direct to your desktop

3. Birdshot
Too busy to keep up with Twitter? Birdshot is a Twitter client stripped down to the basics: send tweets and tell me when I have new responses

4. Destroy Twitter
DestroyTwitter is a robust but compact Twitter application built on the Adobe AIR platform

5. Fedalizr
Feedalizr is a social media desktop client that keeps track of updates from friendfeed, twitter, facebook, Flickr, Twitpic & Jaiku

6. Mixero
The new generation Twitter client for people who value their time and are tired of information noise

7. MySocial AIR
A Twitter client with FriendFeed integration

8. QKTwit
A Twitter client with FriendFeed integration

10. Posty
Posty is a microblogging application which allows interacting with twitter, jaiku, tumblr, friendfeed and identi.ca right from your desktop

11. ScreenTweet
ScreenTweet allows you to post images to your Twitter account by capturing from your screen, dragging and dropping, pasting from clipboard, or browsing your computer

12. ScreenTweetr
Screentweetr enables you to quickly post screenshots to a twitter image service – enter your twitter login credentials, take a screenshot and click upload

13. Seesmic
A desktop client to manage your lifestream from Facebook & multiple Twitter accounts. Create groups and searches and view them any way you like

14. Sideline
Sideline is an application that allows advanced searching and monitoring of the Twitter public timeline

15. Skimmer
Skimmer is an desktop application designed to streamline, beautify, and enhance the experience of participating in your most frequently used social networking activities

16. Snitter
Snitter is “Snook’s Twitter”: an Adobe AIR-powered application for twittering

17. Spaz
Spaz is a free, award-winning Twitter client offering notable features such as access to direct messages and replies, CSS theming, and event sounds

18. Spreadtweet
So, you work at a big corporate, huh? And you’re not allowed to use Twitter…Wouldn’t it be awesome if there were a Twitter tool that looked just like Excel?

19. Statuzer
Statuzer is a multi-platform Twitter Client running through Air

20. Telexer
Telexer, the feed reader for serious news addicts: it’s the lightweight, uncluttered way of getting breaking news

21. T-Messenger
T-Messenger is a very intuitive and powerful Twitter client for every-day users that has a very low memory footprint

22. Tweetdeck
TweetDeck is your personal browser for staying in touch with what’s happening now, connecting you with your contacts across Twitter, Facebook and more

23. TweetDoc
The TwitDoc desktop uploader makes it easy to share your documents and pictures on Twitter

24. Tweetnewz
TweetNewz, a news aggregator and desktop ticker with Twitter integration, keeps readers connected to the news and content they love, all while browsing the web

25. Tweetr
Tweetr is a twitter client that allows you to send and receive twitter messages but has cool features including support for taking photos with your webcam, sending file

26. Twhirl
Twhirl is a social software desktop client for services like Twitter, Seesmic, Friendfeed and identi.ca

27. Twibble
Twibble desktop is a multi account twitter client for Mac, Linux, and Windows

28. Twicker
Twicker is the first (and only) Twitter client that focuses on search.

29. Twitter Local
The TwitterLocal AIR Client allows you to watch as many location-based Twitter feeds as you want

30. Twittm
Follow friends and trends, topics of your interest, and tweet like a maniac.Twittm is fast, clean and unobtrusive

31. Twitulater
Twitulater is an Adobe AIR microblogging client that supports Twitter and Koornk and makes life easier

32. WiURL
WiURL is a great application for shortening any link. It is great for social networks like twitter or pownce

Mac and iPhone Apps

33. Birdbrain
Birdbrain takes snapshots of your Twitter account and tracks changes in your friend and follower lists over time

34. Fring
App for twitter, social networks and Instant Messenger (IM) applications. It supports tremendous number of mobile phones types like iPhone, Nokia, Sony Erricson, HTC, Motorola, LG and many other

35. Incoming!
Incoming! is a Twitter search client designed for power users and social media experts. It lets you cut through the noise and find the tweets that matter to you most

36. Tweetie
A very popular twitter client for iPhone and Mac

37. Twitterrific
Twitterrific is a fun application that lets you both read and publish posts or “tweets” to the Twitter community website

38. TwittShare
Share pictures, music, video, and other files with friends using Twitter

39. iQuickTwitter
QuickSilver + Twitter + iChat + Growl Hack in one. You have to modify some the code with Script Editor to make it work, however it has gotten some good comments.